Heping Zheng

Phone - Lab:   434-924-2948
Fax:                 434-982-1616
e-mail:             dust@iwonka.med.virginia.edu

Structures

Heping has been a coauthor of 35 structures since he joined the Minor Laboratory.


1y89
2004-12-10
annotation

2f96
2005-12-05
annotation

2fgc
2005-12-21
annotation

2g3a
2006-02-17
annotation

2g7u
2006-03-01
annotation

2dg2
2006-03-08
annotation

2goi
2006-04-13
annotation

2i6c
2006-08-28
annotation

2o8n
2006-12-12
annotation

2pc6
2007-03-29
annotation

2pz9
2007-05-17
annotation

2qmo
2007-07-16
annotation

3eef
2008-09-04
annotation

3icc
2009-07-17
annotation

3op4
2010-08-31
annotation

3rro
2011-04-29
annotation

3rsh
2011-05-02
annotation

3t5p
2011-07-27
annotation

3t7b
2011-07-29
annotation

3tzk
2011-09-27
annotation

3tzc
2011-09-27
annotation

3tzh
2011-09-27
annotation

3u09
2011-09-28
annotation

3uwd
2011-12-01
annotation

4i08
2012-11-16
annotation

4iiv
2012-12-20
annotation

4iiu
2012-12-20
annotation

4iin
2012-12-20
annotation

4ijk
2012-12-21
annotation

4jrm
2013-03-21
annotation

4jro
2013-03-21
annotation

4jrh
2013-03-21
annotation

4m3s
2013-08-06
annotation

4nhd
2013-11-04
annotation

4wjz
2014-10-03
annotation

Publications

Heping published 19 papers since he joined the Minor Laboratory.

  1. Zheng H, Chordia MD, Cooper DR, Chruszcz M, Müller P, Sheldrick GM, Minor W
    Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server.
    Nature Protocols 9: 156-70 2014  Times Cited: 7 [View Entrez Listing]

  2. Domagalski MJ, Zheng H, Zimmerman MD, Dauter Z, Wlodawer A, and Minor W
    The Quality and Validation of Structures from Structural Genomics
    Methods in Molecular Biology (Clifton, N.J.) 1091: 297-314 2014  Times Cited: 1 [View Entrez Listing]

  3. Zheng H, Hou J, Zimmerman MD, Wlodawer A, Minor W
    The future of crystallography in drug discovery.
    Expert Opinion on Drug Discovery 9: 125-37 2014  Times Cited: 1 [View Entrez Listing]

  4. Luo HB, Knapik AA, Petkowski JJ, Demas M, Shumilin IA, Zheng H, Chruszcz M, Minor W
    Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus.
    Journal of Structural and Functional Genomics 14: 97-108 2013  Times Cited: 0 [View Entrez Listing]

  5. Zheng H, Filippova EV, Tkaczuk KL, Dworzynski P, Chruszcz M, Porebski PJ, Wawrzak Z, Onopriyenko O, Kudritska M, Grimshaw S, Savchenko A, Anderson WF, Minor W
    Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.
    Journal of Structural and Functional Genomics 13: 15-26 2012  Times Cited: 1 [View Entrez Listing]

  6. Hou J, Wojciechowska K, Zheng H, Chruszcz M, Cooper DR, Cymborowski M, Skarina T, Gordon E, Luo H, Savchenko A, Minor W
    Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis.
    Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 68: 632-7 2012  Times Cited: 1 [View Entrez Listing]

  7. Luo HB, Zheng H, Zimmerman MD, Chruszcz M, Skarina T, Egorova O, Savchenko A, Edwards AM, Minor W
    Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum.
    Journal of Structural Biology 169: 304-11 2010  Times Cited: 8 [View Entrez Listing]

  8. Sledz P, Zheng H, Murzyn K, Chruszcz M, Zimmerman MD, Chordia MD, Joachimiak A, Minor W
    New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization.
    Protein Science 19: 1395-1404 2010  Times Cited: 13 [View Entrez Listing]

  9. Zheng H, Chruszcz M, Lasota P, Lebioda L, Minor W
    Data mining of metal ion environments present in protein structures
    Journal of Inorganic Biochemistry 102(9): 1765-76 2008  Times Cited: 73 [View Entrez Listing]

  10. Chruszcz M, Zimmerman MD, Wang S, Koclega KD, Zheng H, Evdokimova E, Kudritska M, Cymborowski M, Savchenko A, Edwards A, Minor W
    Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1.
    Crystal Growth & Design 8: 4054-4061 2008  Times Cited: 2 [View Entrez Listing]

  11. Chruszcz M, Potrzebowski W, Zimmerman MD, Grabowski M, Zheng H, Lasota P, Minor W
    Analysis of solvent content and oligomeric states in protein crystals--does symmetry matter?
    Protein Science 17: 623-32 2008  Times Cited: 15 [View Entrez Listing]

  12. Shumilin IA, Jha KN, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC
    Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation
    Endocrinology 149: 2108-2120 2008  Times Cited: 20 [View Entrez Listing]

  13. Zheng H, Zuo Y, Wang Y, Chruszcz M, Cymborowski M, Skarina T, Savchenko A, Malhotra A, Minor W
    Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover
    Structure 15: 417-28 2007  Times Cited: 23 [View Entrez Listing]

  14. Dong A, Xu X, Edwards AM, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Graslund S, Hammerstrom M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H
    In situ proteolysis for protein crystallization and structure determination
    Nature Methods 4: 1019-21 2007  Times Cited: 104 [View Entrez Listing]

  15. Zheng H, Gawlicka-Chruszcz A, Cymborowski M, Minor W
    trans-1-Hydroxycyclopentan-2-aminium chloride
    Acta Crystallographica Section E: Structure Reports Online 63: O2697-O2698 2007  Times Cited: 0 

  16. Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W
    Crystal Structures of TM0549 and NE1324--Two Orthologs of E. Coli AHAS Isozyme III Small Regulatory Subunit
    Protein Science 16: 1360-7 2007  Times Cited: 9 [View Entrez Listing]

  17. Zimmerman MD, Chruszcz M, Cymborowski M, Zheng HP, Minor W
    Disodium 4-nitrophenylphosphate hexahydrate
    Acta Crystallographica Section E: Structure Reports Online 62: M884-M886 2006  Times Cited: 1 

  18. Gawlicka-Chruszcz A, Zheng H, Hyacinth M, Cymborowski M, Sabat M, Minor W
    Crystal structure of 2,6-dichlorobenzaldehyde,C7H4Cl2O
    Zeitschrift fur Kristallograhie 221: 545-546 2006  Times Cited: 2 

  19. Chruszcz M, Zheng HP, Cymborowski M, Gawlicka-Chruszcz A, Minor W
    3-(Morpholinium-1-yl)propanesulfonate
    Acta Crystallographica Section E: Structure Reports Online 61: O3190-O3191 2005  Times Cited: 3  [View IUCr Entry]